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  6. CTAB; Cetyltrimethylammonium bromide; Hexadecyltrimethylammonium bromide

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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameHexadecyltrimethylammonium bromide
SynonymsHTAB
CTAB
CTABr
CTMAB
TIMTEC-BB SBB008910
Cetyltrimethylammonium Bromide
Cetyl Trimethyl Ammonium Bromide

Synonyms

HTAB
CTAB
CTABr
CTMAB
TIMTEC-BB SBB008910
Cetyltrimethylammonium Bromide
Cetyl Trimethyl Ammonium Bromide
PALMITYLTRIMETHYLAMMONIUM BROMIDE
Hexadecyltrimethylammonium bromide
TRIMETHYLHEXADECYL-AMMONIUM BROMIDE
N-HEXADECYLTRIMETHYLAMMONIUM BROMIDE
Hexadecyl Trimethyl Ammonium Bromide
N-Hexadecyltrimethylammonium Bromide
N-CETYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE
N,N,N-TRIMETHYLTETRADECYLAMMONIUM BROMIDE
N,N,N-trimethylhexadecan-1-aminium bromide
N-HEXADECYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE
Hexadecanaminium, N,N,N-trimethyl-, bromide
1-Hexadecanaminium,N,N,N-trimethyl-,bromide
CAS57-09-0
EINECS200-311-3
Chemical FormulaC19H42BrN
Molecular Weight364.45
inchiInChI=1/C51H105N.BrH/c1-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49(4)52(50(5)47-44-41-38-35-32-29-26-23-20-17-14-11-8-2)51(6)48-45-42-39-36-33-30-27-24-21-18-15-12-9-3;/h49-51H,7-48H2,1-6H3;1H
Package10 mM * 1 mL;100 mg
PriceEmail to quote
DescriptionsCetrimonium bromide

Cetrimonium bromide

MedChemExpress (MCE)

HY-B1260

57-09-0

CTAB

Descriptions

Cetrimonium bromide

Cetrimonium bromide

MedChemExpress (MCE)

HY-B1260

57-09-0

CTAB
Cetyltrimethylammonium bromide
Hexadecyltrimethylammonium bromide

98.0%

4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture and light)

Room temperature in continental US
may vary elsewhere.

Cetrimonium bromide (CTAB), a quaternary ammonium, is an orally active cationic surfaetant. Cetrimonium bromide has toxicity and anticancer effect. Cetrimonium bromide inhibits cell migration and invasion through modulating the canonical and non-canonical TGF-β signaling pathways. Cetrimonium bromide can be used for DNA extraction.

Cetrimonium bromide (1-5 μM, 24 h) cannot affect growth of SK-HEP-1 cells[1]. Cetrimonium bromide (5 μM, 16-24 h) attenuates cellular migration and invasion of SK-HEP-1cells[1]. Cetrimonium bromide (5 μM, 24 h) inhibits the protein expression of MMP-2 and MMP-9, increases the protein expression of TIMP-1 and TIMP-2 and restrain the protein expression of Rac1, cdc42 and RhoA in SK-HEP-1cells[1]. Cetrimonium bromide (5 μM, 12-72 h) induces apoptosis in human Head and neck cancer (HNC) cells[2].

Cetrimonium bromide (5 mg/kg, Intraperitoneal injection, once a day for five consecutive days) ablated tumor-forming capacity of FaDu cells and delayed growth of established tumors in FaDu cells tumor-bearing mice[2]. Cetrimonium bromide (10-45 mg/kg, Supplemented in drinking water, once a day for 1 year) has subacute and chronic toxicity in the rat[3].

MMP-9 MMP-2

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[1]. Wu T K, et al. Cetrimonium bromide inhibits cell migration and invasion of human hepatic SK-HEP-1 cells through modulating the canonical and non-canonical TGF-β signaling pathways [J]. Anticancer research, 2019, 39(7): 3621-3631. [Content Brief]

[2]. Ito E, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer [J]. Molecular pharmacology, 2009, 76(5): 969-983. [Content Brief]

[3]. Isomaa B, et al. The subacute and chronic toxicity of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, in the rat [J]. Archives of toxicology, 1976, 35: 91-96. [Content Brief]

[4]. Allen G C, et al. A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide [J]. Nature protocols, 2006, 1(5): 2320-2325. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/Cetrimonium-bromide.html
Last Update2025-05-21 16:50:25
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