RE-640 MedChemExpress (MCE)

Product Name	NSC5844
Synonyms	RE640;RE 640; RE640;RE-640;NSC5844; RE-640; RE 640;NSC 5844; NSC-5844;NSC5844 (RE640);N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-
CAS	140926-75-6
EINECS
Chemical Formula	C20H16Cl2N4
Molecular Weight	383.27
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg;100 mg;200 mg
Price	Email to quote
Descriptions	NSC5844 NSC5844 MedChemExpress (MCE) HY-100033 140926-75-6 RE-640 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions NSC5844 NSC5844 MedChemExpress (MCE) HY-100033 140926-75-6 RE-640 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. NSC5844 (RE-640) is a 4-aminoquinoline derivative, with antitumor and antimalarial activity. NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively[1]. NSC5844 (Compound 1) is cytotoxic to P. falciparum, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of P. falciparum, with IC50s of 17 and 27 nM, respectively[2]. Plasmodium \| \| \| \| \| \| \| \| \| \| [1]. Zhang H, et al. Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives. Biomed Pharmacother. 2008 Feb 62(2):65-9. Epub 2007 May 24. [Content Brief] [2]. Vennerstrom JL, et al. Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria. J Med Chem. 1992 May 29 35(11):2129-34. [Content Brief]
Last Update	2025-04-01 14:45:47

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