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  6. 4-Isopropylantipyrine; Isopropylphenazone

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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameIsopropylantipyrine
Synonymspropyphenazone
Isopropylantipyrine
4-isopropylphenazone
4-isopropyl-antipyrin
3,3-Dimethyl-2-Methylene Norcamphone
4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on
4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one

Synonyms

propyphenazone
Isopropylantipyrine
4-isopropylphenazone
4-isopropyl-antipyrin
3,3-Dimethyl-2-Methylene Norcamphone
4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on
4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
4-Isopropyl-2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline
3-Pyrazolin-5-one, 4-isopropyl-2,3-dimethyl-1-phenyl-
4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
1,5-dimethyl-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one
1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on
CAS479-92-5
EINECS207-539-2
Chemical FormulaC14H18N2O
Molecular Weight230.31
inchiInChI=1/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
Package10 mM * 1 mL;500 mg;1 g
PriceEmail to quote
DescriptionsPropyphenazone

Propyphenazone

MedChemExpress (MCE)

HY-A0273

479-92-5

4-Isopropylantipyrine

Descriptions

Propyphenazone

Propyphenazone

MedChemExpress (MCE)

HY-A0273

479-92-5

4-Isopropylantipyrine
Isopropylphenazone

99.85%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Room temperature in continental US
may vary elsewhere.

Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity.

Propyphenazone (4-Isopropylantipyrine
0.7, 7, 70 mg/kg
oral gavage
the entire second week of gestation, days 8-14 of gestation), administered Propyphenazone:Caffeine and Propyphenazone:Paracetamol mixtures with constant 3:1 and 3:5 ratios, causes intrauterine growth retardation but does not increase external or internal congenital anomalies in pregnant Wistar rats[1].

COX

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[1]. F Burdan. Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol. Hum Exp Toxicol. 2004 May
23(5):235-44.
[Content Brief]

[2]. Mohamed F Radwan, et al. Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors. ACS Med Chem Lett. 2014 Jun 23
5(9):983-8.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/Propyphenazone.html
Last Update2025-05-21 16:50:25
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