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  6. VHL Ligand-Linker Conjugates 11; E3 ligase Ligand-Linker Conjugates 11

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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameE3 ligase Ligand-Linker Conjugates 11
Synonyms1835705-61-7
(S,R,S)-AHPC-6-5-6-Cl
(S,R,S)-AHPC-(C3-PEG)2-C6-C
VHL Ligand-Linker Conjugates 11
E3 ligase Ligand-Linker Conjugates 11
(S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride
L-Prolinamide, N-[6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]-1-oxohexyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
CAS1835705-61-7
EINECS
Chemical FormulaC39H61ClN4O6S
Molecular Weight749.44284
inchi
Package50 mg;100 mg
PriceEmail to quote
Descriptions(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

MedChemExpress (MCE)

HY-103608

1835705-61-7

VHL Ligand-Linker Conjugates 11

Descriptions

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

MedChemExpress (MCE)

HY-103608

1835705-61-7

VHL Ligand-Linker Conjugates 11
E3 ligase Ligand-Linker Conjugates 11

99.89%

-80°C, protect from light, stored under nitrogen

Shipping with dry ice.

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

VHL

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[1]. Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11
55(2): 807–810. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_11.html
Last Update2025-05-21 16:50:25
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