Faropenem MedChemExpress (MCE)

Product Name	faropenem sodium
Synonyms	alp201 fropenumsodium faropenem sodium Faropenem sodium hydrate (5r,6s)-6-(1(r)-hydroxyethyl)-2-(2(r)-tetrahydrofuryl)penem-3-carboxylicacid (5R,6S,8R,2′R)-2-(2′-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate sodium salt Synonyms alp201 fropenumsodium faropenem sodium Faropenem sodium hydrate (5r,6s)-6-(1(r)-hydroxyethyl)-2-(2(r)-tetrahydrofuryl)penem-3-carboxylicacid (5R,6S,8R,2′R)-2-(2′-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate sodium salt sodium (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-,monosodiumsalt,(5r-(3(r),5-alpha,6-alpha(r)4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylicaci 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monosodium salt, [5R-[3(R),5α,6α(R)]]- (5r-(3(r),5-alpha,6-alpha(r)))-6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-4-thia-1-azabicyclo(3.2.0) hept-2-ene-2-carboxylic acid monosodium salt
CAS	122547-49-3
EINECS	1592732-453-0
Chemical Formula	C12H14NO5S.Na
Molecular Weight	307.3
inchi	InChI=1/C12H15NO5S.Na/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6;/h5-7,11,14H,2-4H2,1H3,(H,16,17);/q;+1/p-1/t5-,6-,7+,11-;/m1./s1
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg;500 mg
Price	Email to quote
Descriptions	Faropenem sodium Faropenem sodium MedChemExpress (MCE) HY-76260 122547-49-3 98.87% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Faropenem sodium Faropenem sodium MedChemExpress (MCE) HY-76260 122547-49-3 98.87% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis. Faropenem (0.0015-200 μg/mL, 4-7 days) sodium exhibits antituberculosis activity against M. tuberculosis, with MIC of 1.3 μg/mL (with or without clavulanate)[1]. Faropenem (14C radiolabeled, 1 μCi/μL, 30 min) sodium transports across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1[2]. Faropenem (500 mg/kg, p.o., from days 1 to 7 postinfection) sodium reduces bacterial (M. tuberculosis) load in an murine infection model of acute tuberculosis[1]. Faropenem (10-80 mg/kg/day, i.p., 24 h postchallenge at 4-, 6-, and 12-h intervals for 14 days) sodium demonstrates a high level of activity against B. anthracis in the murine postexposure prophylaxis inhalation model[3]. Bacterial[1] In Vitro Faropenem (0.0015-200 μg/mL, 4-7 days) sodium exhibits antituberculosis activity against M. tuberculosis, with MIC of 1.3 μg/mL (with or without clavulanate)[1]. Faropenem (14C radiolabeled, 1 μCi/μL, 30 min) sodium transports across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Faropenem sodium Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Dhar N, et al. Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic. Antimicrob Agents Chemother. 2015 Feb 59(2):1308-19. [Content Brief] [2]. Uchino H, et al. Faropenem transport across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1. Antimicrob Agents Chemother. 2000 Mar 44(3):574-7. [Content Brief] [3]. Gill SC, et al. Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. Antimicrob Agents Chemother. 2010 May 54(5):1678-83. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Faropenem_sodium.html
Last Update	2025-05-21 16:50:25

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