LIN-1418 hydrochloride MedChemExpress (MCE)

Product Name	Sultopride hydrochloride
Synonyms	Stadorf MS-5024 258-641-9 Einecs 245-829-0 Sultopride hydrochloride Sultopride hydrochloride (LIN-1418 hydrochloride) N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-o-anisamide Synonyms Stadorf MS-5024 258-641-9 Einecs 245-829-0 Sultopride hydrochloride Sultopride hydrochloride (LIN-1418 hydrochloride) N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-o-anisamide N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide N-[(1-Ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-benzamidhyd N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-(methyloxy)benzamide n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-ethylsulfonylbenzamidehydroch 1-ethyl-2-({[5-(ethylsulfonyl)-2-methoxybenzoyl]amino}methyl)pyrrolidinium chloride N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride
CAS	23694-17-9
EINECS	245-829-0
Chemical Formula	C17H27ClN2O4S
Molecular Weight	390.93
inchi	InChI=1/C17H26N2O4S.ClH/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3;/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20);1H
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Sultopride hydrochloride Sultopride hydrochloride MedChemExpress (MCE) HY-42849A 23694-17-9 LIN-1418 hydrochloride 99.92% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Sultopride hydrochloride Sultopride hydrochloride MedChemExpress (MCE) HY-42849A 23694-17-9 LIN-1418 hydrochloride 99.92% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p[1]. Thirty-six male Sprague-Dawley rats weighing 180 to 220 g are used in this study. The rats are divided into three groups of 6 each. One group is intraperitoneally injected with Sultopride hydrochloride (100 mg/kg body weight), the second group with sulphide (100 mg/kg body weight), and the third group with normal saline. One hundred minutes after the initial treatments, apomorphine (0.1 mg/kg body weight, dissolved in saline ad libitum) is administered subcutaneously to the three groups, and 20 minutes later the rats are sacrificed. The third group serves as controls[1]. Dopamine D2 receptor[1] In Vivo Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. \| \| \| \| \| \| \| \| \| \| [1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan 20(1):95-9. [Content Brief]
Last Update	2025-04-01 14:45:47

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