YH25448; GNS-1480 MedChemExpress (MCE)

Product Name	N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin-4-yl)phenyl}prop-2-enamide
Synonyms	YH25448 GNS1480 CS-2767 YH-25448 YH 25448 GNS-1480 YH25448 Synonyms YH25448 GNS1480 CS-2767 YH-25448 YH 25448 GNS-1480 YH25448 YH-25448 GNS-1480 GNS1480. YH 25448 GNS 1480 LAZERTINIB Lazertinib Lazertinib(YH25448,GNS-1480) N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin-4-yl)phenyl}prop-2-enamide
CAS	1903008-80-9
EINECS
Chemical Formula	C30H34N8O3
Molecular Weight	554.64
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Lazertinib Lazertinib MedChemExpress (MCE) HY-109061 1903008-80-9 YH25448 Descriptions Lazertinib Lazertinib MedChemExpress (MCE) HY-109061 1903008-80-9 YH25448 GNS-1480 99.07% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Lazertinib (YH25448) is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible third-generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer. Lazertinib (YH25448) is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible third-generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer. Lazertinib targets both T790M mutation and activating EGFR mutations (EGFRm) while sparing wild type[1]. EGFRT790M \| \| \| \| \| \| \| \| \| \| [1]. Byoung Chul Cho, et al. YH25448, a 3rd Generation EGFR-TKI, in Patients with EGFR-TKI-resistant NSCLC: Phase I/II Study Results.
Last Update	2025-04-01 14:45:47

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