2',3'-Dideoxyadenosine MedChemExpress (MCE)

Product Name	2',3'-dideoxyadenosine
Synonyms	DDA Acerola NSC 98700 Dideoxyadenosine 2,3-Dideoxyadenosine 2',3'-dideoxyadenosine 2',3'-dideoxy-adenosin Synonyms DDA Acerola NSC 98700 Dideoxyadenosine 2,3-Dideoxyadenosine 2',3'-dideoxyadenosine 2',3'-dideoxy-adenosin 2',3'-Dideoxy-D-adenosine Didanosine Related CoMpound B 2',3'-DIDEOXYADENOSINE extapure 9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine [(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol [5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl]methanol
CAS	4097-22-7
EINECS	223-853-2
Chemical Formula	C10H13N5O2
Molecular Weight	235.24
inchi	InChI=1/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	2',3'-Dideoxyadenosine 2',3'-Dideoxyadenosine MedChemExpress (MCE) HY-W013441 4097-22-7 99.89% 4°C, protect from light In solvent : -80°C, 6 months Descriptions 2',3'-Dideoxyadenosine 2',3'-Dideoxyadenosine MedChemExpress (MCE) HY-W013441 4097-22-7 99.89% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. 2',3'-Dideoxyadenosine is an inhibitor of HIV replication. Antiretroviral activity. Antiviral efficacy. 2',3'-Dideoxyadenosine inhibits HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC50s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC50s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC50s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC50s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC50 of 24 μM[1]. HIV-1 HIV-2 \| \| \| \| \| \| \| \| \| \| [1]. Balzarini J, et al. Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus. FEBS Lett. 1997 Jun 30 410(2-3):324-8. [Content Brief]
Last Update	2025-04-01 14:45:47

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