YM-529 MedChemExpress (MCE)

Product Name	MINODRONATE
Synonyms	YM 529 BPH 261 Bonoteo Nsc725590 MINODRONATE Minodronic acid (127657-42-5) minodronic acid Synonyms YM 529 BPH 261 Bonoteo Nsc725590 MINODRONATE Minodronic acid (127657-42-5) minodronic acid (1-Hydroxy-2-imidazo[1,2-A]pyridin-3-yl-1-ethyl)-1,1-bisphos phonate PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS- 1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-bis(phosphonic acid) 1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)-1,1-ethanediyl]bis(phosphonic acid) [1-hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl]bis(phosphonic acid)
CAS	127657-42-5;180064-38-4
EINECS	1592732-453-0
Chemical Formula	C9H12N2O7P2
Molecular Weight	322.15
inchi	InChI=1/C9H12N2O7P2/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18)
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Minodronic acid Minodronic acid MedChemExpress (MCE) HY-16322 180064-38-4 YM-529 99.67% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Minodronic acid Minodronic acid MedChemExpress (MCE) HY-16322 180064-38-4 YM-529 99.67% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain. P2X2 Receptor P2X3 Receptor \| \| \| \| \| \| \| \| \| \| [1]. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20 95(10):1354-61. [Content Brief] [2]. Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan 36(1):54-63. [Content Brief]
Last Update	2025-04-01 14:45:47

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