ST 1059 MedChemExpress (MCE)

Product Name	2,5-Dimethoxyphenyl-2-hydroxyethylamine
Synonyms	ST-1059 ST 1059 DESGLYMIDODRINE DE-GLYMIDODRINE Midodrine Related CoMpound A 1-methoxy-2-(3-methoxyanilino)ethanol 1-(2',5'-Dimethoxyphenyl)aminoethanol Synonyms ST-1059 ST 1059 DESGLYMIDODRINE DE-GLYMIDODRINE Midodrine Related CoMpound A 1-methoxy-2-(3-methoxyanilino)ethanol 1-(2',5'-Dimethoxyphenyl)aminoethanol 2-amino-1-(2,5-dimethoxyphenyl)ethanol 2,5-Dimethoxyphenyl-2-hydroxyethylamine 1-(2',5'-DIMETHOXYPHENYL)-2-AMINOETHANOL 2-AMINO-1-(2,5-DIMETHOXY-PHENYL)-ETHANOL Benzenemethanol, a-(aminomethyl)-2,5-dimethoxy- alpha-(Aminomethyl)-2,5-dimethoxybenzenemethanol Benzyl alcohol, alpha-(aminomethyl)-2,5-dimethoxy- 2-(2,5-dimethoxyphenyl)-2-hydroxyethanaminium chloride
CAS	3600-87-1
EINECS
Chemical Formula	C10H15NO3
Molecular Weight	197.23
inchi	InChI=1/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3
Package	5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Desglymidodrine Desglymidodrine MedChemExpress (MCE) HY-114794 3600-87-1 ST 1059 97.33% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Desglymidodrine Desglymidodrine MedChemExpress (MCE) HY-114794 3600-87-1 ST 1059 97.33% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Desglymidodrine (ST 1059), the active metabolite of Midodrine (HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure. Desglymidodrine (ST 1059) (1-1000 μM) affects vein contraction with the pD2 values (negative logarithm of the concentration which causes 50% of the maximum possible effect) of 4.64 (-log mol/L) in dog isolated femoral veins and 4.48 (-log mol/L) in isolated human saphenous veins, respectively[1]. Desglymidodrine (ST 1059) acts on α1A, α1B, α1D in rat and α2A in human adrenoceptor with the pKi values of 5.89, 5.16, 5.78 and 5.83, respectively[2]. α1A-adrenergic receptor 5.89 (pKi) α1B-adrenergic receptor 5.16 (pKi) rat alpha1D-adrenergic receptor 5.78 (pKi) human α2A-adrenoceptor 5.83 (pKi) \| \| \| \| \| \| \| \| \| \| [1]. K Nakayama, et al. Effects of anisotropine methylbromide (Valpin) and its mixture with sulpyrine on vocalization response and spasm of intestine induced by acetylcholine in dogs. Jpn J Pharmacol. 1972 Apr 22(2):215-20. [Content Brief] [2]. Steven ABuckner, et al. ABT-866, a novel α1A-adrenoceptor agonist with antagonist properties at the α1B- and α1D-adrenoceptor subtypes,European Journal of Pharmacology,Volume 449, Issues 1–2,2002,Pages 159-1
Last Update	2025-04-01 14:45:47

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