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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Nametrepibutone
Synonymsaa149
colibil
supacal
aa149
colibil
supacal
trepibutone

Synonyms

aa149
colibil
supacal
aa149
colibil
supacal
trepibutone
Trepibutone
TREPIBUTONE
3-(2,4,5-triethoxybenzoyl)-propionicaci
3-(2,4,5-triethoxybenzoyl)propionicacid
3-(2,4,5-triethoxybenzoyl)propionicacid
3-(2,4,5-triethoxybenzoyl)-propionicaci
4-oxo-4-(2,4,5-triethoxyphenyl)butanoic acid
4-Oxo-4-(2,4,5-triethoxyphenyl)butanoic acid
2,4,5-triethoxy-gamma-oxobenzenebutanoicacid
2,4,5-triethoxy-gamma-oxobenzenebutanoicacid
CAS41826-92-0
EINECS
Chemical FormulaC16H22O6
Molecular Weight310.34
inchiInChI=1/C16H22O6/c1-4-20-13-10-15(22-6-3)14(21-5-2)9-11(13)12(17)7-8-16(18)19/h9-10H,4-8H2,1-3H3,(H,18,19)
Package10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsTrepibutone

Trepibutone

MedChemExpress (MCE)

HY-108283

41826-92-0

AA 149

Descriptions

Trepibutone

Trepibutone

MedChemExpress (MCE)

HY-108283

41826-92-0

AA 149
Supacal

99.83%

4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)

Room temperature in continental US
may vary elsewhere.

Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders.

Trepibutone (1-1000 μM) markedly relaxes the sphincter of Oddi and duodenum[1].

Trepibutone (1-20 mg/kg
i.v. once) dose-dependently increases bile flow[2]. Trepibutone (10 mg/kg
i.v. 3 h after 14C-erythritol injection) stimulates canalicular bile formation without enhancement of water secretion and inhibition of bile reabsorption in the biliary ductules and ducts[2].

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[1]. Hiroshi Saton, et al. RELAXING ACTION OF TREPIBUTONE (AA-149) ON THE ISOLATED SPHINCTER OF ODDI AND SMALL INTESTINE OF RABBITS. The Japanese Journal of Pharmacology. 1981.

[2]. Satoh H, et al. A possible mechanism of choleretic action of 3-(2,4,5-triethoxybenzoyl)-propionic acid (AA-149) in dogs. Eur J Pharmacol. 1978 Mar 1
48(1):125-32.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/trepibutone.html
Last Update2025-05-21 16:50:25
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