L-Cbz-Proline MedChemExpress (MCE)

Product Name	N-Carbobenzyloxy-L-proline
Synonyms	Z-Pro-OH Z-L-Proline CBZ-L-Pro-OH Cbz-L-proline N-Cbz-L-Pro-OH N-Cbz-L-proline carbobenzoxyproline Synonyms Z-Pro-OH Z-L-Proline CBZ-L-Pro-OH Cbz-L-proline N-Cbz-L-Pro-OH N-Cbz-L-proline carbobenzoxyproline N-Carbobenzyloxy-L-proline n-benzyloxycarbonylproline N-cbz-L-proline crystalline N-Benzyloxycarbonyl-L-proline 1-[(benzyloxy)carbonyl]proline 1-[(benzyloxy)carbonyl]-L-proline 1-[(benzyloxy)carbonyl]-D-proline N-Benzyloxycarbonyl-L-proline~Z-Pro-OH N-CBZ-L-Proline N-Carbobenzyloxy-L-proline (2S)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
CAS	1148-11-4
EINECS	214-557-4
Chemical Formula	C13H15NO4
Molecular Weight	249.26
inchi	InChI=1/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/p-1/t11-/m0/s1
Package	10 mM * 1 mL;100 mg;500 mg;1 g;5 g
Price	Email to quote
Descriptions	Carbobenzoxyproline Carbobenzoxyproline MedChemExpress (MCE) HY-Y0588 1148-11-4 L-Cbz-Proline 99.91% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Carbobenzoxyproline Carbobenzoxyproline MedChemExpress (MCE) HY-Y0588 1148-11-4 L-Cbz-Proline 99.91% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research. Carbobenzoxyproline (6 mM 0-10 d pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients[1]. Carbobenzoxyproline (0, 1, 3, 6 mM 1 min pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition[1]. Carbobenzoxyproline (60 mg/kg injection once daily 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model[1]. \| \| \| \| \| \| \| \| \| \| [1]. Lupi A, et al. N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase. Biochim Biophys Acta. 2005 Jun 30 1744(2):157-63. [Content Brief]
Last Update	2025-04-01 14:45:47

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