ChemBK
  • Home
  • Product Category
  • CHN
  1. Home
  2. CAS 2127110-22-7
  3. Supplier List
  4. MedChemExpress (MCE)
  5. Signaling Pathways
  6. JAK-IN-25

Request for quotation








Supplier Contact

Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
QQ
Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
Wechat
Product NamePyrazolo[1,5-a]pyrazine-2-carboxylic acid, 4,5-dihydro-6-[1-[(4-methoxyphenyl)methyl]-1H-pyrazol-4-yl]-4-oxo-, methyl ester
SynonymsPyrazolo[1,5-a]pyrazine-2-carboxylic acid, 4,5-dihydro-6-[1-[(4-methoxyphenyl)methyl]-1H-pyrazol-4-yl]-4-oxo-, methyl ester
CAS2127110-22-7
EINECS
Chemical FormulaC19H17N5O4
Molecular Weight379.37
inchi
Package1 mg;5 mg;10 mg
PriceEmail to quote
DescriptionsJAK-IN-25

JAK-IN-25

MedChemExpress (MCE)

HY-153440

2127110-22-7

98.44%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

JAK-IN-25

JAK-IN-25

MedChemExpress (MCE)

HY-153440

2127110-22-7

98.44%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

JAK-IN-25 (compound 19) is a potent JAK inhibitor with IC50s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2, JAK1, JAK2, JAK3, respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC50 of 28 nM. JAK-IN-25 has the potential for cancer research.

Tyk2 6 nM (IC50) JAK1 21 nM (IC50) JAK2 8 nM (IC50) JAK3 1051 nM (IC50)

| | | |

| | | | | |



[1]. Matthew Frank Brown, et al. Pyrazolo[1,5-a]pyrazin-4-yl derivatives. US20230045252A1.

Supplier Websitehttps://www.medchemexpress.com/jak-in-25.html
Last Update2025-05-21 16:50:25
MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-05-21 16:50:25

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-05-21 16:50:25

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-05-21 16:50:25

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-05-21 16:50:25

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-05-21 16:50:25

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-05-21 16:50:25

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-05-21 16:50:25

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-05-21 16:50:25
  • Home
  • Product Category

© 2015 ChemBK.com All Rights Reserved | Build: 20150530002