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Supplier NameMedChemExpress (MCE)
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Product NamePropargyl-PEG5-alcohol
SynonymsPropargyl-PEG5-alcohol
CAS1036204-60-0
EINECS
Chemical FormulaC13H24O6
Molecular Weight276.32
inchi
Package100 mg;250 mg;1 g;5 g
PriceEmail to quote
DescriptionsPropargyl-PEG5-OH

Propargyl-PEG5-OH

MedChemExpress (MCE)

HY-130147

1036204-60-0

97.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Propargyl-PEG5-OH

Propargyl-PEG5-OH

MedChemExpress (MCE)

HY-130147

1036204-60-0

97.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PEGs

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[1]. Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1.

Last Update2025-04-01 14:45:47
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