Propargyl-PEG1-NH2 MedChemExpress (MCE)

Product Name	2-(2-Propynyloxy)ethylamine
Synonyms	Alkyne-PEG1-NH2;Propargyl-PEG1-NH2;Propargyl-PEG1-amine;2-prop-2-ynoxyethanamine;2-(2-Propynyloxy)ethylamine;2-(2-Propyn-1-yloxy)ethanamine;Ethanamine, 2-(2-propyn-1-yloxy)-
CAS	122116-12-5
EINECS	808-208-0
Chemical Formula	C5H9NO
Molecular Weight	99.13
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Package	100 mg;250 mg;500 mg;1 g;5 g;10 g;25 g
Price	Email to quote
Descriptions	Propargyl-PEG1-NH2 Propargyl-PEG1-NH2 MedChemExpress (MCE) HY-116069 122116-12-5 98.80% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Propargyl-PEG1-NH2 Propargyl-PEG1-NH2 MedChemExpress (MCE) HY-116069 122116-12-5 98.80% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562. [Content Brief]
Last Update	2025-04-01 14:45:47

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