Propargyl-PEG4-O-C1-NHS ester MedChemExpress (MCE)

Product Name	Propargyl-PEG4-O-C1-NHS ester
Synonyms	Propargyl-PEG4-CH2COONHS;Propargyl-PEG5-CH2CO2-NHS;Propargyl-PEG4-O-C1-NHS ester;Propargyl-PEG5-CH2COO-NHS ester;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS	1161883-51-7
EINECS
Chemical Formula	C17H25NO9
Molecular Weight	387.38
inchi
Package	25 mg;50 mg;100 mg;500 mg
Price	Email to quote
Descriptions	Propargyl-PEG4-O-C1-NHS ester Propargyl-PEG4-O-C1-NHS ester MedChemExpress (MCE) HY-130390 1161883-51-7 Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Propargyl-PEG4-O-C1-NHS ester Propargyl-PEG4-O-C1-NHS ester MedChemExpress (MCE) HY-130390 1161883-51-7 Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PEGs Alkyl/ether \| \| \| \| \| \| \| \| \| \| [1]. Kussrow A, et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scatteringinterferometry. Anal Chem. 2009 Jun 15 81(12):4889-97. [Content Brief]
Last Update	2025-04-01 14:45:47

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