NH2-PEG8-acid MedChemExpress (MCE)

Product Name	α-Amine-ω-propionic acid octaethylene glycol
Synonyms	H2N-PEG8-COOH Amino-PEG8-COOH Amino-PEG8-Acid amino-dPEG 8-acid H2N-PEG8-CH2CH2COOH α-AMine-ω-propionic acid octaethylene glycol α-Amine-ω-propionic acid octaethylene glycol Synonyms H2N-PEG8-COOH Amino-PEG8-COOH Amino-PEG8-Acid amino-dPEG 8-acid H2N-PEG8-CH2CH2COOH α-AMine-ω-propionic acid octaethylene glycol α-Amine-ω-propionic acid octaethylene glycol alpha-aMine-oMega-propionic acid octaethylene glycol 27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid
CAS	756526-04-2
EINECS
Chemical Formula	C19H39NO10
Molecular Weight	441.51
inchi
Package	100 mg;250 mg;1 g;5 g
Price	Email to quote
Descriptions	NH2-PEG8-acid NH2-PEG8-acid MedChemExpress (MCE) HY-W019798 756526-04-2 98.0% 4°C, protect from light In solvent : -80°C, 6 months Descriptions NH2-PEG8-acid NH2-PEG8-acid MedChemExpress (MCE) HY-W019798 756526-04-2 98.0% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. Non-cleavable Linker PEGs \| \| \| \| \| \| \| \| \| \| [1]. Michael Nathaniel ALONSO, et al. Antibody adjuvant conjugates. WO2018009916A1. [2]. "An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562." [Content Brief]
Supplier Website	https://www.medchemexpress.com/nh2-peg8-acid.html
Last Update	2025-05-21 16:50:25

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