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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameEthanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)
SynonymsPEG3-Tos
PEG4-Tos
Hydroxy-PEG3-Tos
Tos-PEG3-alcohol
Tos-PEG4-alcohol
Triethylene glycol p-toluenesulfonate
Triethylene glycol p-toluenesulfonate

Synonyms

PEG3-Tos
PEG4-Tos
Hydroxy-PEG3-Tos
Tos-PEG3-alcohol
Tos-PEG4-alcohol
Triethylene glycol p-toluenesulfonate
Triethylene glycol p-toluenesulfonate
2-(2-(2-Hydroxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate
Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate)
CAS77544-68-4
EINECS
Chemical FormulaC13H20O6S
Molecular Weight304.36
inchi
Package1 g;5 g;10 g;25 g
PriceEmail to quote
DescriptionsTos-PEG3

Tos-PEG3

MedChemExpress (MCE)

HY-23408

77544-68-4

98.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Tos-PEG3

Tos-PEG3

MedChemExpress (MCE)

HY-23408

77544-68-4

98.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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[1]. Noël M, et al. Solid Supports for the Synthesis of 3'-Aminooxy Deoxy- or Ribo-oligonucleotides and Their 3'-Conjugation by Oxime Ligation.J Org Chem. 2019 Nov 15
84(22):14854-14860.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/tos-peg3.html
Last Update2025-05-21 16:50:25
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