Benzyl-PEG2-azide MedChemExpress (MCE)

Product Name	Benzyl-PEG2-Azide
Synonyms	Benzyl-PEG2-N3;Benzyl-PEG2-Azide;2-(2-azidoethoxy)ethoxymethylbenzene
CAS	1260001-87-3
EINECS
Chemical Formula	C11H15N3O2
Molecular Weight	221.26
inchi
Package	100 mg;250 mg;1 g
Price	Email to quote
Descriptions	Benzyl-PEG2-azide Benzyl-PEG2-azide MedChemExpress (MCE) HY-130188 1260001-87-3 99.12% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Benzyl-PEG2-azide Benzyl-PEG2-azide MedChemExpress (MCE) HY-130188 1260001-87-3 99.12% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. \| \| \| \| \| \| \| \| \| \| [1]. Steinebach C, et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm. 2019 May 28 10(6):1037-1041. [Content Brief]
Last Update	2025-04-01 14:45:47

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