Mal-amido-PEG8-NHS ester MedChemExpress (MCE)

Product Name	α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol)
Synonyms	Mal-PEG8-NHS Maleimide-PEG8-NHS Mal-NH-PEG8-NHS ester Maleimide PEG8 succinimidyl ester α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol) Α-MALEIMIDOPROPIONYL-Ω-SUCCINIMIDYL-8(ETHYLENE GLYCOL) Synonyms Mal-PEG8-NHS Maleimide-PEG8-NHS Mal-NH-PEG8-NHS ester Maleimide PEG8 succinimidyl ester α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol) Α-MALEIMIDOPROPIONYL-Ω-SUCCINIMIDYL-8(ETHYLENE GLYCOL) alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) N-[27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide 31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester
CAS	756525-93-6
EINECS
Chemical Formula	C30H47N3O15
Molecular Weight	689.71
inchi
Package	5 mg;10 mg;25 mg;50 mg;100 mg;250 mg;1 g
Price	Email to quote
Descriptions	Mal-amido-PEG8-NHS ester Mal-amido-PEG8-NHS ester MedChemExpress (MCE) HY-W040133 756525-93-6 98.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Mal-amido-PEG8-NHS ester Mal-amido-PEG8-NHS ester MedChemExpress (MCE) HY-W040133 756525-93-6 98.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs Alkyl/ether \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562. [Content Brief]
Last Update	2025-04-01 14:45:47

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