Bis-PEG10-NHS ester MedChemExpress (MCE)

Product Name	Bis-PEG10-NHS ester
Synonyms	Bis-PEG10-NHS ester;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid, 1,34-bis(2,5-dioxo-1-pyrrolidinyl) ester
CAS	2221949-02-4
EINECS
Chemical Formula	C32H52N2O18
Molecular Weight	752.76
inchi
Package	5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Bis-PEG10-NHS ester Bis-PEG10-NHS ester MedChemExpress (MCE) HY-130824 2221949-02-4 95.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Bis-PEG10-NHS ester Bis-PEG10-NHS ester MedChemExpress (MCE) HY-130824 2221949-02-4 95.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PEGs Alkyl/ether Cleavable Linker \| \| \| \| \| \| \| \| \| \| [1]. John L. Magnani, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1
Last Update	2025-04-01 14:45:47

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