C4-HSL; N-Butyryl-L-homoserine lactone MedChemExpress (MCE)

Product Name
Synonyms	C4-HSL N-butyryl-L-Homoserine Butyryl-L-hoMoserine lactone N-butyryl-L-Homoserine lactone N-(2-oxotetrahydrofuran-3-yl)butanamide (S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI Synonyms C4-HSL N-butyryl-L-Homoserine Butyryl-L-hoMoserine lactone N-butyryl-L-Homoserine lactone N-(2-oxotetrahydrofuran-3-yl)butanamide (S)-N-(2-Oxotetrahydrofuran-3-yl)butyraMide C4-HSL, N-Butyryl-L-hoMoserine lactone, PAI N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide
CAS	67605-85-0
EINECS
Chemical Formula	C8H13NO3
Molecular Weight	171.195
inchi
Package	100 mg;250 mg;1 g;5 g
Price	Email to quote
Descriptions	N-Butanoyl-L-homoserine lactone N-Butanoyl-L-homoserine lactone MedChemExpress (MCE) HY-114816 67605-85-0 C4-HSL Descriptions N-Butanoyl-L-homoserine lactone N-Butanoyl-L-homoserine lactone MedChemExpress (MCE) HY-114816 67605-85-0 C4-HSL N-Butyryl-L-homoserine lactone 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa. The dissociation constant (Kd value) of aptamer binding to N-Butanoyl-L-homoserine lactone (C4-HSL) is 28.47 nM[2]. Cleavable Linker \| \| \| \| \| \| \| \| \| \| [1]. Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1 [2]. Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19 14(2):e0212041. [Content Brief] [3]. Feng Sun, et al. Advance of the diversity of bacterial quorum sensing and quorum quenching. National Natural Science Foundation of China. Published online 9 October 2018.
Last Update	2025-04-01 14:45:47

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