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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product Name1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl)
SynonymsN-(5-Hydroxypentyl)maleimide;1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl)
CAS180608-78-0
EINECS
Chemical FormulaC9H13NO3
Molecular Weight183.2
inchi
Package10 mg;25 mg;50 mg;100 mg;500 mg
PriceEmail to quote
DescriptionsN-(5-Hydroxypentyl)maleimide

N-(5-Hydroxypentyl)maleimide

MedChemExpress (MCE)

HY-130818

180608-78-0

99.89%

-20°C, stored under nitrogen *In solvent : -80°C, 6 months

Descriptions

N-(5-Hydroxypentyl)maleimide

N-(5-Hydroxypentyl)maleimide

MedChemExpress (MCE)

HY-130818

180608-78-0

99.89%

-20°C, stored under nitrogen *In solvent : -80°C, 6 months
-20°C, 1 month (stored under nitrogen)

Room temperature in continental US
may vary elsewhere.

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812)).

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker)[1].

Non-cleavable Linker

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[1]. Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.

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