Guanidinobiotin hydrobromide MedChemExpress (MCE)

Product Name	2-Iminobiotin hydrobromide
Synonyms	2-Iminobiotin hydrobromide;JKIJLCYOCQWMQL-UFLZEWODSA-N;5-((3aR,6S,6aS)-2-Amino-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl)pentanoic acid hydrobromide
CAS	76985-52-9
EINECS
Chemical Formula	C10H18BrN3O2S
Molecular Weight	324.23782
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	2-Iminobiotin hydrobromide 2-Iminobiotin hydrobromide MedChemExpress (MCE) HY-118700A 76985-52-9 Guanidinobiotin hydrobromide 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions 2-Iminobiotin hydrobromide 2-Iminobiotin hydrobromide MedChemExpress (MCE) HY-118700A 76985-52-9 Guanidinobiotin hydrobromide 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage. Application of low concentrations of 2-Iminobiotin (2-IB 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control[1]. iNOS \| \| \| \| \| \| \| \| \| \| [1]. Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28 204(2):962-8. [Content Brief] [2]. Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11 8:971. [Content Brief]
Last Update	2025-04-01 14:45:47

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