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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameAcid-apeg8-acid n-c3-maleimide
SynonymsN-Mal-N-bis(PEG4-acid);Mal-N-bis(PEG4-C2-acid);Acid-apeg8-acid n-c3-maleimide;4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-
CAS2100306-52-1
EINECS
Chemical FormulaC29H48N2O15
Molecular Weight664.7
inchi
Package50 mg;100 mg
PriceEmail to quote
DescriptionsMal-N-bis(PEG4-C2-acid)

Mal-N-bis(PEG4-C2-acid)

MedChemExpress (MCE)

HY-140530

2100306-52-1

98.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Mal-N-bis(PEG4-C2-acid)

Mal-N-bis(PEG4-C2-acid)

MedChemExpress (MCE)

HY-140530

2100306-52-1

98.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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