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Supplier NameMedChemExpress (MCE)
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Product NameBromoacetamido-PEG4-NHS ester
SynonymsBromoacetamido-PEG4-NHS ester
CAS1260139-70-5
EINECS
Chemical FormulaC17H27N2O9Br
Molecular Weight483.3
inchi
Package50 mg;100 mg;250 mg
PriceEmail to quote
DescriptionsBromoacetamido-PEG4-NHS ester

Bromoacetamido-PEG4-NHS ester

MedChemExpress (MCE)

HY-141387

1260139-70-5

95.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Bromoacetamido-PEG4-NHS ester

Bromoacetamido-PEG4-NHS ester

MedChemExpress (MCE)

HY-141387

1260139-70-5

95.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Bromoacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs Alkyl/ether

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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