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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product Name3-(4-(3,6,9,12-Tetraoxapentadec-14-yn-1-yloxy)phenyl)-6-methyl-1,2,4,5-tetrazine
SynonymsMethyltetrazine-PEG5-Alkyne;3-(4-(3,6,9,12-Tetraoxapentadec-14-yn-1-yloxy)phenyl)-6-methyl-1,2,4,5-tetrazine;1,2,4,5-Tetrazine, 3-methyl-6-[4-(3,6,9,12-tetraoxapentadec-14-yn-1-yloxy)phenyl]-
CAS1802907-97-6
EINECS
Chemical FormulaC20H26N4O5
Molecular Weight402.44
inchi
Package10 mg;25 mg;50 mg;100 mg;250 mg
PriceEmail to quote
DescriptionsMethyltetrazine-PEG5-alkyne

Methyltetrazine-PEG5-alkyne

MedChemExpress (MCE)

HY-141275

1802907-97-6

98.0%

4°C, stored under nitrogen *In solvent : -80°C, 6 months

Descriptions

Methyltetrazine-PEG5-alkyne

Methyltetrazine-PEG5-alkyne

MedChemExpress (MCE)

HY-141275

1802907-97-6

98.0%

4°C, stored under nitrogen *In solvent : -80°C, 6 months
-20°C, 1 month (stored under nitrogen)

Room temperature in continental US
may vary elsewhere.

Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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