Methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate MedChemExpress (MCE)

Product Name	Methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate
Synonyms	HO-PEG2-COOMe Hydroxy-PEG2-methyl ester Hydroxy-PEG2-C2-methyl ester Methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate METHYL 3-[2-(2-HYDROXYETHOXY)ETHOXY]PROPANOATE Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]-, methyl ester
CAS	457897-73-3
EINECS
Chemical Formula	C8H16O5
Molecular Weight	192.21
inchi
Package	100 mg;250 mg;500 mg;1 g
Price	Email to quote
Descriptions	Hydroxy-PEG2-C2-methyl ester Hydroxy-PEG2-C2-methyl ester MedChemExpress (MCE) HY-141240 457897-73-3 Methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate 98.48% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Hydroxy-PEG2-C2-methyl ester Hydroxy-PEG2-C2-methyl ester MedChemExpress (MCE) HY-141240 457897-73-3 Methyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate 98.48% Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Hydroxy-PEG2-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs Alkyl/ether \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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