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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameHydroxy-PEG3-t-butyl acetate
SynonymsHydroxy-PEG3-t-butyl acetate
CAS518044-31-0
EINECS
Chemical FormulaC12H24O6
Molecular Weight264.31536
inchi
Package100 mg;250 mg;1 g;5 g;10 g
PriceEmail to quote
DescriptionsHydroxy-PEG3-CH2-Boc

Hydroxy-PEG3-CH2-Boc

MedChemExpress (MCE)

HY-141209

518044-31-0

97.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Hydroxy-PEG3-CH2-Boc

Hydroxy-PEG3-CH2-Boc

MedChemExpress (MCE)

HY-141209

518044-31-0

97.0%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Hydroxy-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs Alkyl/ether

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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