SPDP-PEG4-NHS ester MedChemExpress (MCE)

Product Name	SPDP-PEG4-NHS ester
Synonyms	SDPD-PEG4-NHS NHS-PEG4-SPDP SPDP-PEG4-NHS Opss-peg(4)-nhs SPDP-PEG4-NHS ester SPDP-dPEG(R)4-NHS ester 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 17-oxo-19-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester Synonyms SDPD-PEG4-NHS NHS-PEG4-SPDP SPDP-PEG4-NHS Opss-peg(4)-nhs SPDP-PEG4-NHS ester SPDP-dPEG(R)4-NHS ester 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 17-oxo-19-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(pyridin-2-yldisulfanyl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CAS	1334177-95-5
EINECS
Chemical Formula	C23H33N3O9S2
Molecular Weight	559.65
inchi
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	SPDP-PEG4-NHS ester SPDP-PEG4-NHS ester MedChemExpress (MCE) HY-130195 1334177-95-5 95.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions SPDP-PEG4-NHS ester SPDP-PEG4-NHS ester MedChemExpress (MCE) HY-130195 1334177-95-5 95.0% Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs Alkyl/ether \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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