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Supplier NameMedChemExpress (MCE)
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Product NameAcid-PEG5-NHS ester
SynonymsAcid-PEG5-NHS ester
CAS1343476-41-4
EINECS
Chemical FormulaC18H29NO11
Molecular Weight435.42
inchi
Package25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsAcid-C2-PEG4-C2-NHS ester

Acid-C2-PEG4-C2-NHS ester

MedChemExpress (MCE)

HY-130436

1343476-41-4

98.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

Acid-C2-PEG4-C2-NHS ester

Acid-C2-PEG4-C2-NHS ester

MedChemExpress (MCE)

HY-130436

1343476-41-4

98.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs Alkyl/ether

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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