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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameSuccinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
SynonymsSuccinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate
CAS158913-22-5
EINECS
Chemical FormulaC18H23N3O5S2
Molecular Weight425.52
inchi
Package25 mg;50 mg;100 mg;250 mg
PriceEmail to quote
DescriptionsSPDP-C6-NHS ester

SPDP-C6-NHS ester

MedChemExpress (MCE)

HY-124377

158913-22-5

98.09%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

SPDP-C6-NHS ester

SPDP-C6-NHS ester

MedChemExpress (MCE)

HY-124377

158913-22-5

98.09%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Alkyl/ether

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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