PC Methyltetrazine-PEG4-NHS carbonate ester MedChemExpress (MCE)

Product Name	PC Methyltetrazine-PEG4-NHS carbonate ester
Synonyms	PC Methyltetrazine-PEG4-NHS carbonate ester Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-methoxy-4-[[16-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-4-oxo-8,11,14-trioxa-5-azahexadec-1-yl]oxy]-2-nitrophenyl]ethyl ester
CAS	2055736-28-0
EINECS
Chemical Formula	C35H43N7O14
Molecular Weight	785.75
inchi
Package	25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	PC Methyltetrazine-PEG4-NHS carbonate ester PC Methyltetrazine-PEG4-NHS carbonate ester MedChemExpress (MCE) HY-140141 2055736-28-0 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions PC Methyltetrazine-PEG4-NHS carbonate ester PC Methyltetrazine-PEG4-NHS carbonate ester MedChemExpress (MCE) HY-140141 2055736-28-0 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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