MK 462 MedChemExpress (MCE)

Product Name	Rizatriptan Benzoate
Synonyms	MAXALT MK-462 MK-0462 Rizatrimptan Rizatriptan Benzoate RIZATRIPTAN BENZOATE Rizatrimptan Benzoate Synonyms MAXALT MK-462 MK-0462 Rizatrimptan Rizatriptan Benzoate RIZATRIPTAN BENZOATE Rizatrimptan Benzoate RIZATRIPTANE BENZOATE Acid Bixente triptans Rizatriptan monobenzoate N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H- N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine N,N-DIMETHYL-5-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-INDOLE-3-ETHANAMINE, BENZOATE n,n-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1h-indol-3-yl]ethylamine benzoate N,N-dimethy1-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine monobenzoate
CAS	145202-66-0
EINECS	604-465-6
Chemical Formula	C22H25N5O2
Molecular Weight	391.47
inchi	InChI=1/C15H19N5/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3
Package	10 mM * 1 mL;5 mg;10 mg;50 mg
Price	Email to quote
Descriptions	Rizatriptan benzoate Rizatriptan benzoate MedChemExpress (MCE) HY-B0206 145202-66-0 MK 462 99.94% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Rizatriptan benzoate Rizatriptan benzoate MedChemExpress (MCE) HY-B0206 145202-66-0 MK 462 99.94% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Rizatriptan benzoate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system. Rizatriptan benzoate (0.3-3 mg/kg, iv, every 10 min for 1 h) inhibits the electrical stimulation of the dura mater induced pain response in the trigeminal nucleus caudalis of rats models, exhibits anti-migraine effect[2]. 5-HT1 Receptor \| \| \| \| \| \| \| \| \| \| [1]. Sciberras DG, et al. Initial human experience with MK-462 (rizatriptan): a novel 5-HT1D agonist. Br J Clin Pharmacol. 1997 Jan 43(1):49-54. [Content Brief] [2]. Cumberbatch MJ, et al. Rizatriptan has central antinociceptive effects against durally evoked responses. Eur J Pharmacol. 1997 Jun 5 328(1):37-40. [Content Brief]
Last Update	2025-04-01 14:45:47

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