Dde Biotin-PEG4-alkyne MedChemExpress (MCE)

Product Name	Dde Biotin-PEG4-alkyne
Synonyms	Dde Biotin-PEG4-alkyne Dde Biotin-PEG4-Alkyne Biotin-peg(4)-dde-alkyne 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl]hexahydro-2-oxo-, (3aR,4R,6aS)-rel-
CAS	1802908-00-4
EINECS
Chemical Formula	C32H50N4O8S
Molecular Weight	650.83
inchi
Package	100 mg;250 mg
Price	Email to quote
Descriptions	Dde Biotin-PEG4-alkyne Dde Biotin-PEG4-alkyne MedChemExpress (MCE) HY-140924 1802908-00-4 97.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Dde Biotin-PEG4-alkyne Dde Biotin-PEG4-alkyne MedChemExpress (MCE) HY-140924 1802908-00-4 97.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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