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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameBromo-PEG6-azid
SynonymsBr-PEG6-N3;Azido-PEG6-Br;Bro-PEG7-azido;Bromo-PEG6-azid;N3-PEG6-CH2CH2Br;Bromo-PEG6-azide;1-?Azido-?20-?bromo-?3,?6,?9,?12,?15,?18-?hexaoxaicosane
CAS2062663-64-1
EINECS
Chemical FormulaC14H29BrN3O6+
Molecular Weight415.30056
inchi
Package10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsBromo-PEG6-azide

Bromo-PEG6-azide

MedChemExpress (MCE)

HY-140823

2062663-64-1

95.0%

4°C, protect from light *In solvent : -80°C, 6 months

Descriptions

Bromo-PEG6-azide

Bromo-PEG6-azide

MedChemExpress (MCE)

HY-140823

2062663-64-1

95.0%

4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)

Room temperature in continental US
may vary elsewhere.

Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bromo-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/bromo-peg6-azide.html
Last Update2025-05-21 16:50:25
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