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Supplier NameMedChemExpress (MCE)
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Product NameBiotin-peg6-nhs ester
SynonymsBiotin-PEG6-SPA
Biotin-peg6-nhs ester
(+)-Biotin-PEG6-NHS Ester
4,7,10,13,16,19-Hexaoxa-22-azaheptacosanoic acid, 27-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-23-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CAS2055045-04-8
EINECS
Chemical FormulaC29H48N4O12S
Molecular Weight676.77602
inchi
Package5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
DescriptionsBiotin-PEG6-NHS ester

Biotin-PEG6-NHS ester

MedChemExpress (MCE)

HY-140890

2055045-04-8

98.0%

-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months

Descriptions

Biotin-PEG6-NHS ester

Biotin-PEG6-NHS ester

MedChemExpress (MCE)

HY-140890

2055045-04-8

98.0%

-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)

Room temperature in continental US
may vary elsewhere.

Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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