N-(Boc-PEG1)-N-bis(PEG2-propargyl) MedChemExpress (MCE)

Product Name	N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Synonyms	N-(Boc-PEG1)-N-bis(PEG2-propargyl);5,11,14-Trioxa-2,8-diazaheptadec-16-ynoic acid, 8-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
CAS	2100306-63-4
EINECS
Chemical Formula	C23H40N2O7
Molecular Weight	456.57
inchi
Package	25 mg;50 mg;100 mg;250 mg
Price	Email to quote
Descriptions	N-(Boc-PEG1)-N-bis(PEG2-propargyl) N-(Boc-PEG1)-N-bis(PEG2-propargyl) MedChemExpress (MCE) HY-140090 2100306-63-4 97.0% 4°C, protect from light In solvent : -80°C, 6 months Descriptions N-(Boc-PEG1)-N-bis(PEG2-propargyl) N-(Boc-PEG1)-N-bis(PEG2-propargyl) MedChemExpress (MCE) HY-140090 2100306-63-4 97.0% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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