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Supplier NameMedChemExpress (MCE)
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Product NameMal-amido-PEG12-NHS
SynonymsMal-amido-PEG12-NHS
CAS2101722-60-3
EINECS
Chemical FormulaC38H63N3O19
Molecular Weight865.92
inchi
Package25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsMal-amido-PEG12-NHS ester

Mal-amido-PEG12-NHS ester

MedChemExpress (MCE)

HY-140977

2101722-60-3

95.48%

-20°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months

Descriptions

Mal-amido-PEG12-NHS ester

Mal-amido-PEG12-NHS ester

MedChemExpress (MCE)

HY-140977

2101722-60-3

95.48%

-20°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (stored under nitrogen, away from moisture)

Room temperature in continental US
may vary elsewhere.

Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

PEGs

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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