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Supplier NameMedChemExpress (MCE)
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product NameAzidoacetic acid NHS ester
SynonymsNHS-Ac-N3
NHS-Azide
Aeide-C1-NHS ester
AZIDOACETIC ACID NHS ESTER
Azidoacetic acid NHS ester
(2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
2,5-Pyrrolidinedione, 1-[(azidoacetyl)oxy]-

Synonyms

NHS-Ac-N3
NHS-Azide
Aeide-C1-NHS ester
AZIDOACETIC ACID NHS ESTER
Azidoacetic acid NHS ester
(2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
2,5-Pyrrolidinedione, 1-[(azidoacetyl)oxy]-
2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester
Azidoacetic acid NHS ester,2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester
CAS824426-32-6
EINECS
Chemical FormulaC6H6N4O4
Molecular Weight198.14
inchi
Package25 mg;50 mg;100 mg;250 mg;1 g
PriceEmail to quote
DescriptionsAeide-C1-NHS ester

Aeide-C1-NHS ester

MedChemExpress (MCE)

HY-140755

824426-32-6

98.0%

-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months

Descriptions

Aeide-C1-NHS ester

Aeide-C1-NHS ester

MedChemExpress (MCE)

HY-140755

824426-32-6

98.0%

-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)

Room temperature in continental US
may vary elsewhere.

Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Aeide-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Alkyl/ether

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/aeide-c1-nhs-ester.html
Last Update2025-05-21 16:50:25
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