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Supplier NameMedChemExpress (MCE)
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Product NamePC Alkyne-PEG4-NHS carbonate ester
SynonymsPC Alkyne-PEG4-NHS ester;PC Alkyne-PEG4-NHS carbonate ester;Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-methoxy-2-nitro-4-[(4-oxo-8,11,14,17-tetraoxa-5-azaeicos-19-yn-1-yl)oxy]phenyl]ethyl ester
CAS1802907-98-7
EINECS
Chemical FormulaC29H39N3O14
Molecular Weight653.63
inchi
Package25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsPC Alkyne-PEG4-NHS ester

PC Alkyne-PEG4-NHS ester

MedChemExpress (MCE)

HY-140139

1802907-98-7

95.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

PC Alkyne-PEG4-NHS ester

PC Alkyne-PEG4-NHS ester

MedChemExpress (MCE)

HY-140139

1802907-98-7

95.0%

Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337. [Content Brief]

Last Update2025-04-01 14:45:47
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