Azido-PEG8-hydrazide MedChemExpress (MCE)

Product Name	Azido-PEG8-hydrazide
Synonyms	Azido-PEG8-hydrazide
CAS	2353410-11-2
EINECS
Chemical Formula	C19H39N5O9
Molecular Weight	481.55
inchi
Package	5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Azido-PEG8-hydrazide Azido-PEG8-hydrazide MedChemExpress (MCE) HY-140815 2353410-11-2 96.11% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Azido-PEG8-hydrazide Azido-PEG8-hydrazide MedChemExpress (MCE) HY-140815 2353410-11-2 96.11% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Last Update	2025-04-01 14:45:47

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