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Supplier NameMedChemExpress (MCE)
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Product NamePC Mal-NHS carbonate ester
SynonymsPC Mal-NHS carbonate ester
1-(4-(4-((2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-4-oxobutoxy)-5-methoxy-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate
Carbonic acid, 1-[4-[4-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-4-oxobutoxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-1-pyrrolidinyl ester
CAS1408057-91-9
EINECS
Chemical FormulaC24H26N4O12
Molecular Weight562.48
inchi
Package5 mg;10 mg
PriceEmail to quote
DescriptionsPC Mal-NHS carbonate ester

PC Mal-NHS carbonate ester

MedChemExpress (MCE)

HY-140140

1408057-91-9

95.0%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

PC Mal-NHS carbonate ester

PC Mal-NHS carbonate ester

MedChemExpress (MCE)

HY-140140

1408057-91-9

95.0%

Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337. [Content Brief]

Last Update2025-04-01 14:45:47
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