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Supplier NameMedChemExpress (MCE)
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Product Nameendo-BCN-PEG4-Val-Cit-PAB-MMAE
Synonymsendo-BCN-PEG4-Val-Cit-PAB-MMAE
CAS2762519-08-2
EINECS
Chemical Formula
Molecular Weight
inchi
Package1 mg
PriceEmail to quote
Descriptionsendo-BCN-PEG4-Val-Cit-PAB-MMAE

endo-BCN-PEG4-Val-Cit-PAB-MMAE

MedChemExpress (MCE)

HY-141155

2762519-08-2

99.95%

4°C, stored under nitrogen *The compound is unstable in solutions, freshly prepared is recommended.

Room temperature in continental US

Descriptions

endo-BCN-PEG4-Val-Cit-PAB-MMAE

endo-BCN-PEG4-Val-Cit-PAB-MMAE

MedChemExpress (MCE)

HY-141155

2762519-08-2

99.95%

4°C, stored under nitrogen *The compound is unstable in solutions, freshly prepared is recommended.

Room temperature in continental US
may vary elsewhere.

endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337. [Content Brief]

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