Clobetasone butyrate MedChemExpress (MCE)

Product Name	clobetasone butyrate
Synonyms	SN 203 Emovate Eumovate Molivate CCI 5537 Cloptison UNII-8U0H6XI6EO Synonyms SN 203 Emovate Eumovate Molivate CCI 5537 Cloptison UNII-8U0H6XI6EO )-pregn-5-en-20-one Clobetasone butyrate -Hydroxytestosterone clobetasone butyrate Clobetasone 17-butyrate )-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione butyrate (16beta)-21-chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butanoate 21-Chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione butyrate 21-Chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate )-17-Acetyloxy-3-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-, butyrate Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16beta)- Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16-beta)- )-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide-d3
CAS	25122-57-0
EINECS	246-635-9
Chemical Formula	C26H32ClFO5
Molecular Weight	478.98
inchi	InChI=1/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
Package	10 mM * 1 mL;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Clobetasone butyrate Clobetasone butyrate MedChemExpress (MCE) HY-B1616 25122-57-0 99.80% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Clobetasone butyrate Clobetasone butyrate MedChemExpress (MCE) HY-B1616 25122-57-0 99.80% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic?dermatitis and psoriasis. Clobetasone butyrate (application on the skin 0.05% 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy[1]. IC50: glucocorticoid[1] In Vivo Clobetasone butyrate (application on the skin 0.05% 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Large white domestic pig[1] \| \| \| \| \| \| \| \| \| \| [1]. Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy. [Content Brief] [2]. Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.
Last Update	2025-04-01 14:45:47

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