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Supplier NameMedChemExpress (MCE)
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Product Nameβ-Estradiol-6-one 6-(O-carboxymethyloxime)
Synonymsβ-Estradiol-6-one 6-(O-carboxymethyloxime)
CAS35048-47-6
EINECS
Chemical FormulaC20H25NO5
Molecular Weight359.42
inchi
Package5 mg
PriceEmail to quote
Descriptionsβ-Estradiol-6-one 6-(O-carboxymethyloxime)

β-Estradiol-6-one 6-(O-carboxymethyloxime)

MedChemExpress (MCE)

HY-133407

35048-47-6

99.67%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

β-Estradiol-6-one 6-(O-carboxymethyloxime)

β-Estradiol-6-one 6-(O-carboxymethyloxime)

MedChemExpress (MCE)

HY-133407

35048-47-6

99.67%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker
one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Alkyl-Chain

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[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct
36:553-562 [Content Brief]

Last Update2025-04-01 14:45:47
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