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Supplier NameMedChemExpress (MCE)
Contactsales
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Emailsales@medchemexpress.com; tech@medchemexpress.com
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Product Name-
SynonymsBCN-PEG4-acid;BCN-endo-PEG4-COOH;BCN-PEG4-ACID (ENDO);rel-1-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid
CAS1881221-47-1
EINECS
Chemical FormulaC22H35NO8
Molecular Weight441.52
inchi
Package5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
Descriptionsendo-BCN-PEG4-acid

endo-BCN-PEG4-acid

MedChemExpress (MCE)

HY-135971

1881221-47-1

99.27%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

endo-BCN-PEG4-acid

endo-BCN-PEG4-acid

MedChemExpress (MCE)

HY-135971

1881221-47-1

99.27%

Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Cleavable Linker

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[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May
16(5):315-337. [Content Brief]

Last Update2025-04-01 14:45:47
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