Thalidomide-NH-PEG2-C2-NH-Boc MedChemExpress (MCE)

Product Name	Thalidomide-NH-PEG2-C2-NH-Boc
Synonyms	Thalidomide-NH-PEG2-NH-Boc Thalidomide-NH-PEG2-C2-NH-Boc Carbamic acid, N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester
CAS	2097509-40-3
EINECS
Chemical Formula	C24H32N4O8
Molecular Weight	504.53
inchi
Package	100 mg;250 mg
Price	Email to quote
Descriptions	Thalidomide-NH-PEG2-C2-NH-Boc Thalidomide-NH-PEG2-C2-NH-Boc MedChemExpress (MCE) HY-130853 2097509-40-3 98.37% -20°C, stored under nitrogen In solvent : -80°C, 6 months Descriptions Thalidomide-NH-PEG2-C2-NH-Boc Thalidomide-NH-PEG2-C2-NH-Boc MedChemExpress (MCE) HY-130853 2097509-40-3 98.37% -20°C, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (stored under nitrogen) Room temperature in continental US may vary elsewhere. Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology. dBRD9 (0-1 μM) exerts a potent anti-proliferative effect, exceeding non-degrading probe potencies in excesses of 10 to 100 fold[1]. Cereblon \| \| \| \| \| \| \| \| \| \| [1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15 56(21):5738-5743. [Content Brief]
Supplier Website	https://www.medchemexpress.com/thalidomide-nh-peg2-c2-nh-boc.html
Last Update	2025-05-21 16:50:25

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