BAY2353 olamine MedChemExpress (MCE)

Product Name	Niclosamide ethanolamine salt
Synonyms	BAYER73 Mollutox Luomiecide Clonitralide Bayluscid[R] niclosamide-olamine NICLOSAMIDE ETHANOLAMINE Synonyms BAYER73 Mollutox Luomiecide Clonitralide Bayluscid[R] niclosamide-olamine NICLOSAMIDE ETHANOLAMINE Phenasal ethanolamine salt Ethanolamine salt Niclosamide Niclosamide ethanolamine salt 2'',5-DICHLORO-4''-NITROSALICYLANILIDE(NICLOSAMIDE) 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide 2',5-Dichloro-4'-nitrosalicylanilide 2-aminoethanol salt 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide 2-aminoethanol salt
CAS	1420-04-8
EINECS	215-811-7
Chemical Formula	C15H15Cl2N3O5
Molecular Weight	388.2
inchi	InChI=1/C13H8Cl2N2O4.C2H7NO/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15;3-1-2-4/h1-6,18H,(H,16,19);4H,1-3H2
Package	10 mM * 1 mL;50 mg;100 mg;500 mg
Price	Email to quote
Descriptions	Niclosamide olamine Niclosamide olamine MedChemExpress (MCE) HY-B0497C 1420-04-8 BAY2353 olamine 99.44% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Niclosamide olamine Niclosamide olamine MedChemExpress (MCE) HY-B0497C 1420-04-8 BAY2353 olamine 99.44% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research. Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells. Niclosamide olamine (0.6 nM-46 µM) treatment inhibits adrenocortical carcinoma cellular proliferation in BD140A, SW-13, and NCI-H295R cells[3].Niclosamide olamine (0.05-5 μM, 24 h) treatment inhibits STAT3-mediated luciferase reporter activity in HeLa cells [4].Niclosamide olamine (10 μM) treatment inhibits virus replication in Vero E6 cells[5]. Niclosamide sodium (oral gavage 100 mg/kg, 200 mg/kg once a week 8 weeks) treatment inhibits adrenocortical carcinoma tumor growth in vivo[3]. \| \| \| \| \| \| \| \| \| \| [1]. P Andrews, et al. The biology and toxicology of molluscicides, Bayluscide. Pharmacol Ther. 1982 19(2):245-95. [Content Brief] [2]. Wei Chen, et al. Niclosamide: Beyond an antihelminthic drug. Cell Signal. 2018 Jan 41:89-96. [Content Brief] [3]. Kei Satoh, et al. Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma. Clin Cancer Res. 2016 Jul 15 22(14):3458-66. [Content Brief] [4]. Xiaomei Ren, et al. Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. ACS Med Chem Lett. 2010 Sep 7 1(9):454-9. [Content Brief] [5]. Chang-Jer Wu, et al. Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide. Antimicrob Agents Chemother. 2004 Jul 48(7):2693-6. [Content Brief]
Last Update	2025-04-01 14:45:47

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