Nattokinase, Natto fermentation MedChemExpress (MCE)

Product Name	Nattokinase
Synonyms	Nattokinase NattoesseHaruno-Ogawa LiposomalNATTOKINASE,NATTOKINASENanoEmulsion,NanoActiveNATTOKINASE, 4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic
CAS	133876-92-3
EINECS
Chemical Formula	C20H23BCl2N2O9
Molecular Weight	517.122
inchi
Package	5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Nattokinase, Natto fermentation Nattokinase, Natto fermentation MedChemExpress (MCE) HY-P2373 133876-92-3 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Nattokinase, Natto fermentation Nattokinase, Natto fermentation MedChemExpress (MCE) HY-P2373 133876-92-3 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases. Nattokinase dissolves 94% blood clot at ten minutes and degrades the fibrin clot after two hours of incubation[2]. Product Information Molecular weight: 27728 Da (a single-chain polypeptide enzyme composed of 275 amino acids in a fixed arrangement) Acidity and alkalinity: relatively stable in neutral or alkaline environment (pH 7.0 ~12.0), extremely unstable when pH enzyme activity will not be completely lost even under acidic conditions. Temperature: sensitive to high temperature, with better stability below 37°C, and it will be quickly inactivated due to protein denaturation when the temperature is higher than 60°C. Freeze-thaw: After repeated freeze-thaw cycles for 5 times, 95% of the original activity can still be retained. Instructions Nattokinase (150-250 mg/kg oral gavage twice daily for 2 days) exhibits fibrinolytic activity and dissolves blood clots in vivo[3]. \| \| \| \| \| \| \| \| \| \| [1]. Weng Y, et, al. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. Int J Mol Sci. 2017 Feb 28 18(3):523. [Content Brief] [2]. Chandrasekaran SD, et, al. Exploring the In Vitro Thrombolytic Activity of Nattokinase From a New Strain Pseudomonas aeruginosa CMSS. Jundishapur J Microbiol. 2015 Oct 26 8(10): e23567. [Content Brief] [3]. Xu J, et, al. Thrombolytic effects in vivo of nattokinase in a carrageenan-induced rat model of thrombosis. Acta Haematol. 2014 132(2): 247-53. [Content Brief]
Last Update	2025-04-01 14:45:47

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